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Pharmacokinetics and pharmacodynamics of dexmedetomidine‐induced vasoconstriction in healthy volunteers
AIMS: Alpha‐2 agonists are direct peripheral vasoconstrictors, which achieve these effects by activating vascular smooth muscle alpha‐2 adrenoceptors. The impact of this response during dexmedetomidine infusion remains poorly quantified. Our goal was to investigate the pharmacokinetic (PK) and pharm...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5980451/ https://ncbi.nlm.nih.gov/pubmed/29495085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13571 |
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