Study of GABA in Healthy Volunteers: Pharmacokinetics and Pharmacodynamics

Preclinical studies show that GABA exerts anti-diabetic effects in rodent models of type 1 diabetes. Because little is known about its absorption and effects in humans, we investigated the pharmacokinetics and pharmacodynamics of GABA in healthy volunteers. Twelve subjects were subjected to an open-...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Li, Junfeng, Zhang, Zhaoyun, Liu, Xiaoxia, Wang, Yi, Mao, Fei, Mao, Junjun, Lu, Xiaolan, Jiang, Dongdong, Wan, Yun, Lv, Jia-Ying, Cao, Guoying, Zhang, Jing, Zhao, Naiqing, Atkinson, Mark, Greiner, Dale L., Prud'homme, Gerald J., Jiao, Zheng, Li, Yiming, Wang, Qinghua
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639630/
https://ncbi.nlm.nih.gov/pubmed/26617516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00260
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