Human secreted proteins SLURP‐1 and SLURP‐2 control the growth of epithelial cancer cells via interactions with nicotinic acetylcholine receptors

BACKGROUND AND PURPOSE: Nicotinic acetylcholine receptors (nAChRs) are a promising target for development of new anticancer therapies. Here we have investigated the effects of the endogenous human proteins SLURP‐1 and SLURP‐2, antagonists of nAChRs, on human epithelial cancer cells. EXPERIMENTAL APP...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Pharmacol
Prif Awduron: Lyukmanova, E N, Bychkov, M L, Sharonov, G V, Efremenko, A V, Shulepko, M A, Kulbatskii, D S, Shenkarev, Z O, Feofanov, A V, Dolgikh, D A, Kirpichnikov, M P
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Themed Section: Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980222/
https://ncbi.nlm.nih.gov/pubmed/29505672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14194
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