Human secreted proteins SLURP‐1 and SLURP‐2 control the growth of epithelial cancer cells via interactions with nicotinic acetylcholine receptors

BACKGROUND AND PURPOSE: Nicotinic acetylcholine receptors (nAChRs) are a promising target for development of new anticancer therapies. Here we have investigated the effects of the endogenous human proteins SLURP‐1 and SLURP‐2, antagonists of nAChRs, on human epithelial cancer cells. EXPERIMENTAL APP...

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Detalles Bibliográficos
Publicado en:Br J Pharmacol
Main Authors: Lyukmanova, E N, Bychkov, M L, Sharonov, G V, Efremenko, A V, Shulepko, M A, Kulbatskii, D S, Shenkarev, Z O, Feofanov, A V, Dolgikh, D A, Kirpichnikov, M P
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Themed Section: Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980222/
https://ncbi.nlm.nih.gov/pubmed/29505672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14194
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