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Human secreted proteins SLURP‐1 and SLURP‐2 control the growth of epithelial cancer cells via interactions with nicotinic acetylcholine receptors

BACKGROUND AND PURPOSE: Nicotinic acetylcholine receptors (nAChRs) are a promising target for development of new anticancer therapies. Here we have investigated the effects of the endogenous human proteins SLURP‐1 and SLURP‐2, antagonists of nAChRs, on human epithelial cancer cells. EXPERIMENTAL APP...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Lyukmanova, E N, Bychkov, M L, Sharonov, G V, Efremenko, A V, Shulepko, M A, Kulbatskii, D S, Shenkarev, Z O, Feofanov, A V, Dolgikh, D A, Kirpichnikov, M P
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980222/
https://ncbi.nlm.nih.gov/pubmed/29505672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14194
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