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β-Amyloid peptides enhance α-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

Alzheimer's disease and Parkinson's disease are associated with the cerebral accumulation of β-amyloid and α-synuclein, respectively. Some patients have clinical and pathological features of both diseases, raising the possibility of overlapping pathogenetic pathways. We generated transgeni...

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Autors principals: Masliah, Eliezer, Rockenstein, Edward, Veinbergs, Isaac, Sagara, Yutaka, Mallory, Margaret, Hashimoto, Makoto, Mucke, Lennart
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC59799/
https://ncbi.nlm.nih.gov/pubmed/11572944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211412398
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