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Inactivation of SREBP-1a Phosphorylation Prevents Fatty Liver Disease in Mice: Identification of Related Signaling Pathways by Gene Expression Profiles in Liver and Proteomes of Peroxisomes

The key lipid metabolism transcription factor sterol regulatory element-binding protein (SREBP)-1a integrates gene regulatory effects of hormones, cytokines, nutrition and metabolites as lipids, glucose, or cholesterol via phosphorylation by different mitogen activated protein kinase (MAPK) cascades...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Knebel, Birgit, Hartwig, Sonja, Jacob, Sylvia, Kettel, Ulrike, Schiller, Martina, Passlack, Waltraud, Koellmer, Cornelia, Lehr, Stefan, Müller-Wieland, Dirk, Kotzka, Jorg
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979561/
https://ncbi.nlm.nih.gov/pubmed/29587401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19040980
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