The JAK2 GGCC (46/1) Haplotype in Myeloproliferative Neoplasms: Causal or Random?

The germline JAK2 haplotype known as “GGCC or 46/1 haplotype” (haplotype(GGCC_46/1)) consists of a combination of single nucleotide polymorphisms (SNPs) mapping in a region of about 250 kb, extending from the JAK2 intron 10 to the Insulin-like 4 (INLS4) gene. Four main SNPs (rs3780367, rs10974944, r...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Anelli, Luisa, Zagaria, Antonella, Specchia, Giorgina, Albano, Francesco
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979434/
https://ncbi.nlm.nih.gov/pubmed/29641446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041152
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