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The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms
BACKGROUND: Myeloproliferative neoplasms constitute a group of diverse chronic myeloid malignancies that share pathogenic features such as acquired mutations in the JAK2, TET2, CBL and MPL genes. There are recent reports that a JAK2 gene haplotype (GGCC or 46/1) confers susceptibility to JAK2 mutati...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Ferrata Storti Foundation
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046267/ https://ncbi.nlm.nih.gov/pubmed/21173100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.034488 |
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