The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms

BACKGROUND: Myeloproliferative neoplasms constitute a group of diverse chronic myeloid malignancies that share pathogenic features such as acquired mutations in the JAK2, TET2, CBL and MPL genes. There are recent reports that a JAK2 gene haplotype (GGCC or 46/1) confers susceptibility to JAK2 mutati...

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Detalhes bibliográficos
Main Authors: Olcaydu, Damla, Rumi, Elisa, Harutyunyan, Ashot, Passamonti, Francesco, Pietra, Daniela, Pascutto, Cristiana, Berg, Tiina, Jäger, Roland, Hammond, Emma, Cazzola, Mario, Kralovics, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046267/
https://ncbi.nlm.nih.gov/pubmed/21173100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.034488
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