Testosterone-Dependent miR-26a-5p and let-7g-5p Act as Signaling Mediators to Regulate Sperm Apoptosis via Targeting PTEN and PMAIP1

Recent evidence suggests that testosterone deficiency can dramatically decrease the quality of sperm. MicroRNAs (miRNAs) are conserved mediators of post-transcriptional gene regulation in eukaryotes. However, the systemic regulation and function of miRNAs in sperm quality decline induced by testoste...

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Udgivet i:Int J Mol Sci
Main Authors: Ma, Jideng, Fan, Yu, Zhang, Jinwei, Feng, Siyuan, Hu, Zihui, Qiu, Wanling, Long, Keren, Jin, Long, Tang, Qianzi, Wang, Xun, Zhou, Qi, Gu, Yiren, Xiao, Weihang, Liu, Lingyan, Li, Xuewei, Li, Mingzhou
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979296/
https://ncbi.nlm.nih.gov/pubmed/29670053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041233
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