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Testosterone-Dependent miR-26a-5p and let-7g-5p Act as Signaling Mediators to Regulate Sperm Apoptosis via Targeting PTEN and PMAIP1

Recent evidence suggests that testosterone deficiency can dramatically decrease the quality of sperm. MicroRNAs (miRNAs) are conserved mediators of post-transcriptional gene regulation in eukaryotes. However, the systemic regulation and function of miRNAs in sperm quality decline induced by testoste...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ma, Jideng, Fan, Yu, Zhang, Jinwei, Feng, Siyuan, Hu, Zihui, Qiu, Wanling, Long, Keren, Jin, Long, Tang, Qianzi, Wang, Xun, Zhou, Qi, Gu, Yiren, Xiao, Weihang, Liu, Lingyan, Li, Xuewei, Li, Mingzhou
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979296/
https://ncbi.nlm.nih.gov/pubmed/29670053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041233
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