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Testosterone-Dependent miR-26a-5p and let-7g-5p Act as Signaling Mediators to Regulate Sperm Apoptosis via Targeting PTEN and PMAIP1

Recent evidence suggests that testosterone deficiency can dramatically decrease the quality of sperm. MicroRNAs (miRNAs) are conserved mediators of post-transcriptional gene regulation in eukaryotes. However, the systemic regulation and function of miRNAs in sperm quality decline induced by testoste...

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Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Ma, Jideng, Fan, Yu, Zhang, Jinwei, Feng, Siyuan, Hu, Zihui, Qiu, Wanling, Long, Keren, Jin, Long, Tang, Qianzi, Wang, Xun, Zhou, Qi, Gu, Yiren, Xiao, Weihang, Liu, Lingyan, Li, Xuewei, Li, Mingzhou
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979296/
https://ncbi.nlm.nih.gov/pubmed/29670053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041233
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