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Effect of the monoclonal antibody TRC105 in combination with Sunitinib on renal tumor derived endothelial cells

Anti-angiogenic therapy is an important strategy to limit growth, development and expansion of solid tumors. However, resistance to VEGF-targeting agents may develop, due to activation of alternative pro-angiogenic pathways, indicating the need of multiple target strategy. Here we obtained tumor end...

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Pubblicato in:Oncotarget
Autori principali: Brossa, Alessia, Buono, Lola, Bussolati, Benedetta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5978257/
https://ncbi.nlm.nih.gov/pubmed/29854307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25206
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