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Sunitinib but not VEGF blockade inhibits cancer stem cell endothelial differentiation

Different mechanisms of angiogenesis and vasculogenesis are involved in the development of the tumor vasculature. Among them, cancer stem cells are known to contribute to tumor vasculogenesis through their direct endothelial differentiation. Here, we investigated the effect of anti-angiogenic therap...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Brossa, Alessia, Grange, Cristina, Mancuso, Letizia, Annaratone, Laura, Satolli, Maria Antonietta, Mazzone, Massimiliano, Camussi, Giovanni, Bussolati, Benedetta
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484457/
https://ncbi.nlm.nih.gov/pubmed/25948774
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