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Propensity for cis-proline formation in unfolded proteins

In unfolded proteins, peptide bonds involving Pro residues exist in an equilibrium between the minor cis and major trans conformations. Folded proteins predominantly contain trans-Pro bonds, and slow cis-trans Pro isomerization in the unfolded state is often found to be a rate limiting step in prote...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Alderson, T. Reid, Lee, Jung Ho, Charlier, Cyril, Ying, Jinfa, Bax, Ad
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977977/
https://ncbi.nlm.nih.gov/pubmed/29064600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700548
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