Cyclooxygenase-2 Promotes Amyloid Plaque Deposition in a Mouse Model of Alzheimer’s Disease Neuropathology

Several epidemiologic studies have reported that cyclooxygenase (COX) inhibitors prevent/delay the onset of Alzheimer’s disease (AD). Recent experimental studies suggest that these compounds can also diminish amyloid-β (Aβ) neuropathology in rodent models of AD. To explore the relationship of COX ex...

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Gepubliceerd in:Gene Expr
Hoofdauteurs: Xiang, Zhongmin, Ho, Lap, Yemul, Shrishailam, Zhao, Zhong, Pompl, Patrick, Kelley, Kevin, Dang, Anju, Qing, Weiping, Teplow, David, Pasinetti, Giulio Maria
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cognizant Communication Corporation 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977525/
https://ncbi.nlm.nih.gov/pubmed/12450219
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