Overexpression of mTOR and p(240–244)S6 in IDH1 Wild-Type Human Glioblastomas Is Predictive of Low Survival

PI3K/Akt/mTOR pathway activation is a hallmark of high-grade gliomas, which prompted clinical trials for the use of PI3K and mTOR inhibitors. However, the poor results in the original trials suggested that better patient profiling was needed for such drugs. Thus, accurate and reproducible monitoring...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Histochem Cytochem
Main Authors: Machado, Luis Eduardo, Alvarenga, Arthur William, da Silva, Fernanda Ferreira, Roffé, Martín, Begnami, Maria Dirlei, Torres, Luís Fernando Bleggi, da Cunha, Isabela Werneck, Martins, Vilma Regina, Hajj, Glaucia Noeli Maroso
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977438/
https://ncbi.nlm.nih.gov/pubmed/29328863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155417750838
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados