Induction of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and Inflammation-Associated Colon Cancer

Nitric oxide (NO) plays an established role in numerous physiological and pathological processes, but the specific cellular sources of NO in disease pathogenesis remain unclear, preventing the implementation of NO-related therapy. Argininosuccinate lyase (ASL) is the only enzyme able to produce argi...

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Published in:Cell Rep
Main Authors: Stettner, Noa, Rosen, Chava, Bernshtein, Biana, Gur-Cohen, Shiri, Frug, Julia, Silberman, Alon, Sarver, Alona, Carmel-Neiderman, Narin N., Eilam, Raya, Biton, Inbal, Pevsner-Fischer, Meirav, Zmora, Niv, Brandis, Alexander, Bahar Halpern, Keren, Mazkereth, Ram, di Bernardo, Diego, Brunetti-Pierri, Nicola, Premkumar, Muralidhar H., Dank, Gillian, Nagamani, Sandesh C.S., Jung, Steffen, Harmelin, Alon, Erez, Ayelet
Format: Artigo
Language:Inglês
Published: Cell Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976577/
https://ncbi.nlm.nih.gov/pubmed/29768197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.053
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