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Endothelial Smoothened-dependent Hedgehog Signaling is Not Required for Sonic Hedgehog Induced Angiogenesis or Ischemic Tissue Repair

Sonic Hedgehog (Shh) signaling induces neovascularization and angiogenesis. It is not known whether hedgehog signaling pathway in endothelial cells is essential to angiogenesis. Smoothened (Smo) transduces hedgehog signaling across the cell membrane. This study assessed whether endothelial Smoothene...

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Publicado en:Lab Invest
Main Authors: Gupta, Rajesh, Mackie, Alexander R., Misener, Sol, Liu, Lijun, Losordo, Douglas W., Kishore, Raj
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976512/
https://ncbi.nlm.nih.gov/pubmed/29453401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-018-0028-5
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