Endothelial Smoothened-dependent Hedgehog Signaling is Not Required for Sonic Hedgehog Induced Angiogenesis or Ischemic Tissue Repair

Sonic Hedgehog (Shh) signaling induces neovascularization and angiogenesis. It is not known whether hedgehog signaling pathway in endothelial cells is essential to angiogenesis. Smoothened (Smo) transduces hedgehog signaling across the cell membrane. This study assessed whether endothelial Smoothene...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Lab Invest
Prif Awduron: Gupta, Rajesh, Mackie, Alexander R., Misener, Sol, Liu, Lijun, Losordo, Douglas W., Kishore, Raj
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976512/
https://ncbi.nlm.nih.gov/pubmed/29453401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-018-0028-5
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