Enhanced Angiogenic and Cardiomyocyte Differentiation Capacity of Epigenetically Reprogrammed Mouse and Human Endothelial Progenitor Cells Augments their Efficacy for Ischemic Myocardial Repair

RATIONALE: While Bone-marrow endothelial progenitor cell based therapies (BM-EPC) improve the symptoms in patients with ischemic heart disease their limited plasticity and decreased function in patients with existing heart disease limits the full benefit of EPC therapy for cardiac regenerative medic...

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Autori principali: Thal, Melissa A., Krishnamurthy, Prasanna, Mackie, Alexander R., Hoxha, Eneda, Lambers, Erin, Verma, Suresh, Ramirez, Veronica, Qin, Gangjian, Losordo, Douglas W., Kishore, Raj
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406600/
https://ncbi.nlm.nih.gov/pubmed/22589372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.270462
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