Histone Deacetylase 1 Deficiency Impairs Differentiation and Electrophysiological Properties of Cardiomyocytes Derived from induced Pluripotent Cells

Epigenetic and chromatin modifications play particularly important roles in Embryonic and induced Pluripotent Stem cells (ES and iPS cells) allowing for the cells to both differentiate and dedifferentiate back to a pluripotent state. We analyzed how the loss of a key chromatin modifying enzyme, hist...

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Bibliografski detalji
Glavni autori: Hoxha, Eneda, Lambers, Erin, Xie, Hehuang, De Andrade, Alexandre, Krishnamurthy, Prasanna, Wasserstrom, John A., Ramirez, Veronica, Thal, Melissa, Verma, Suresh K., Soares, Marcelo B., Kishore, Raj
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479375/
https://ncbi.nlm.nih.gov/pubmed/22915496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1209
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