Histone Deacetylase 1 Deficiency Impairs Differentiation and Electrophysiological Properties of Cardiomyocytes Derived from induced Pluripotent Cells

Epigenetic and chromatin modifications play particularly important roles in Embryonic and induced Pluripotent Stem cells (ES and iPS cells) allowing for the cells to both differentiate and dedifferentiate back to a pluripotent state. We analyzed how the loss of a key chromatin modifying enzyme, hist...

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Main Authors: Hoxha, Eneda, Lambers, Erin, Xie, Hehuang, De Andrade, Alexandre, Krishnamurthy, Prasanna, Wasserstrom, John A., Ramirez, Veronica, Thal, Melissa, Verma, Suresh K., Soares, Marcelo B., Kishore, Raj
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479375/
https://ncbi.nlm.nih.gov/pubmed/22915496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1209
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