Kinetic and structural comparison of a protein’s cotranslational folding and refolding pathways

Precise protein folding is essential for the survival of all cells, and protein misfolding causes a number of diseases that lack effective therapies, yet the general principles governing protein folding in the cell remain poorly understood. In vivo, folding can begin cotranslationally and protein qu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Adv
Prif Awduron: Samelson, Avi J., Bolin, Eric, Costello, Shawn M., Sharma, Ajeet K., O’Brien, Edward P., Marqusee, Susan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Association for the Advancement of Science 2018
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976279/
https://ncbi.nlm.nih.gov/pubmed/29854950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aas9098
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