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Causal Impact of Type 2 Diabetes Mellitus on Cerebral Small Vessel Disease: A Mendelian Randomization Analysis

BACKGROUND AND PURPOSE—: The relationship between type 2 diabetes mellitus (T2D) and cerebral small vessel disease (CSVD) is unclear. We aimed to examine the causal effect of T2D, fasting glucose levels, and higher insulin resistance on CSVD using Mendelian randomization. METHODS—: Five CSVD phenoty...

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Publicat a:Stroke
Autors principals: Liu, Junfeng, Rutten-Jacobs, Loes, Liu, Ming, Markus, Hugh S., Traylor, Matthew
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976219/
https://ncbi.nlm.nih.gov/pubmed/29686024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.117.020536
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