Association of MTHFR C677T Genotype With Ischemic Stroke Is Confined to Cerebral Small Vessel Disease Subtype

Elevated plasma homocysteine levels are associated with stroke. However, this might be a reflection of bias or confounding because trials have failed to demonstrate an effect from homocysteine lowering in stroke patients, although a possible benefit has been suggested in lacunar stroke. Genetic stud...

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Veröffentlicht in:Stroke
Hauptverfasser: Rutten-Jacobs, Loes C.A., Traylor, Matthew, Adib-Samii, Poneh, Thijs, Vincent, Sudlow, Cathie, Rothwell, Peter M., Boncoraglio, Giorgio, Dichgans, Martin, Meschia, James, Maguire, Jane, Levi, Christopher, Rost, Natalia S., Rosand, Jonathan, Hassan, Ahamad, Bevan, Steve, Markus, Hugh S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760380/
https://ncbi.nlm.nih.gov/pubmed/26839351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.011545
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