Genetic Architecture of White Matter Hyperintensities Differs in Hypertensive and Nonhypertensive Ischemic Stroke

BACKGROUND AND PURPOSE—: Epidemiological studies suggest that white matter hyperintensities (WMH) are extremely heritable, but the underlying genetic variants are largely unknown. Pathophysiological heterogeneity is known to reduce the power of genome-wide association studies (GWAS). Hypertensive an...

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Veröffentlicht in:Stroke
Hauptverfasser: Adib-Samii, Poneh, Devan, William, Traylor, Matthew, Lanfranconi, Silvia, Zhang, Cathy R., Cloonan, Lisa, Falcone, Guido J., Radmanesh, Farid, Fitzpatrick, Kaitlin, Kanakis, Allison, Rothwell, Peter M., Sudlow, Cathie, Boncoraglio, Giorgio B., Meschia, James F., Levi, Chris, Dichgans, Martin, Bevan, Steve, Rosand, Jonathan, Rost, Natalia S., Markus, Hugh S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306538/
https://ncbi.nlm.nih.gov/pubmed/25550368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.114.006849
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