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Microfabrication of liver and heart tissues for drug development

Drug-induced liver- and cardiotoxicity remain among the leading causes of preclinical and clinical drug attrition, marketplace drug withdrawals and black-box warnings on marketed drugs. Unfortunately, animal testing has proven to be insufficient for accurately predicting drug-induced liver- and card...

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Detalhes bibliográficos
Publicado no:Philos Trans R Soc Lond B Biol Sci
Main Authors: Brown, Grace E., Khetani, Salman R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974448/
https://ncbi.nlm.nih.gov/pubmed/29786560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2017.0225
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