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Linking drug target and pathway activation for effective therapy using multi-task learning

Despite the abundance of large-scale molecular and drug-response data, the insights gained about the mechanisms underlying treatment efficacy in cancer has been in general limited. Machine learning algorithms applied to those datasets most often are used to provide predictions without interpretation...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Yang, Mi, Simm, Jaak, Lam, Chi Chung, Zakeri, Pooya, van Westen, Gerard J. P., Moreau, Yves, Saez-Rodriguez, Julio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974390/
https://ncbi.nlm.nih.gov/pubmed/29844324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25947-y
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