Meclofenamic Acid Reduces Reactive Oxygen Species Accumulation and Apoptosis, Inhibits Excessive Autophagy, and Protects Hair Cell-Like HEI-OC1 Cells From Cisplatin-Induced Damage

Hearing loss is the most common sensory disorder in humans, and a significant number of cases is due to the ototoxicity of drugs such as cisplatin that cause hair cell (HC) damage. Thus, there is great interest in finding agents and mechanisms that protect HCs from ototoxic drug damage. It has been...

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Pubblicato in:Front Cell Neurosci
Autori principali: Li, He, Song, Yongdong, He, Zuhong, Chen, Xiaoyun, Wu, Xianmin, Li, Xiaofei, Bai, Xiaohui, Liu, Wenwen, Li, Boqin, Wang, Shanshan, Han, Yuechen, Xu, Lei, Zhang, Daogong, Li, Jianfeng, Chai, Renjie, Wang, Haibo, Fan, Zhaomin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974247/
https://ncbi.nlm.nih.gov/pubmed/29875633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00139
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