PARP-1-modulated AIF translocation is involved in streptomycin-induced cochlear hair cell death

CONCLUSION: SM-induced dose- and location-dependent cochlear hair cell death in vitro. AIF might be translocated from mitochondria to nucleus and cytoplasm within SM-treated hair cells. The translocation of AIF might be modulated by PARP-1. OBJECTIVE: Streptomycin (SM), one of the widely used aminog...

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Publicado en:Acta Otolaryngol
Autores principales: Song, Yongdong, Fan, Zhaomin, Bai, Xiaohui, Liu, Wenwen, Han, Yuechen, Xu, Lei, Wang, Mingming, Li, Jianfeng, Zheng, Qingyin, Zhang, Daogong, Wang, Haibo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861077/
https://ncbi.nlm.nih.gov/pubmed/26963167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00016489.2016.1143968
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