The Kinase Complex mTOR Complex 2 Promotes the Follicular Migration and Functional Maturation of Differentiated Follicular Helper CD4(+) T Cells During Viral Infection

Follicular helper CD4(+) T (T(FH)) cells are critical for optimal B-cell-mediated humoral immunity by initiating, fueling, and sustaining germinal center reactions. The differentiation of T(FH) cells relies on multiple intrinsic and extrinsic factors; however, the details by which these factors are...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hao, Yaxing, Wang, Yifei, Liu, Xiaobing, Yang, Xia, Wang, Pengcheng, Tian, Qin, Bai, Qiang, Chen, Xiangyu, Li, Zhirong, Wu, Jialin, Xie, Zhunyi, Zhou, Xinyuan, Zhou, Yuyang, Yin, Zhinan, Wu, Yuzhang, Ye, Lilin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974104/
https://ncbi.nlm.nih.gov/pubmed/29875775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01127
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