QuantumClone: clonal assessment of functional mutations in cancer based on a genotype-aware method for clonal reconstruction

MOTIVATION: In cancer, clonal evolution is assessed based on information coming from single nucleotide variants and copy number alterations. Nonetheless, existing methods often fail to accurately combine information from both sources to truthfully reconstruct clonal populations in a given tumor samp...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Deveau, Paul, Colmet Daage, Leo, Oldridge, Derek, Bernard, Virginie, Bellini, Angela, Chicard, Mathieu, Clement, Nathalie, Lapouble, Eve, Combaret, Valerie, Boland, Anne, Meyer, Vincent, Deleuze, Jean-Francois, Janoueix-Lerosey, Isabelle, Barillot, Emmanuel, Delattre, Olivier, Maris, John M, Schleiermacher, Gudrun, Boeva, Valentina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972665/
https://ncbi.nlm.nih.gov/pubmed/29342233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty016
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