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Erythropoietin Treatment Exacerbates Moderate Injury after Hypoxia-Ischemia in Neonatal Superoxide Dismutase Transgenic Mice

The neonatal brain is highly susceptible to oxidative stress as developing endogenous antioxidant mechanisms are overwhelmed. In the neonate, superoxide dismutase (SOD) overexpression worsens hypoxic-ischemic injury due to H(2)O(2) accumulation in the brain. Erythropoietin (EPO) is upregulated in 2...

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Detalles Bibliográficos
Publicado en:Dev Neurosci
Main Authors: Sheldon, R. Ann, Windsor, Christine, Lee, Byong Sop, Arteaga Cabeza, Olatz, Ferriero, Donna M.
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972513/
https://ncbi.nlm.nih.gov/pubmed/28445874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000472710
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