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Erythropoietin Treatment Exacerbates Moderate Injury after Hypoxia-Ischemia in Neonatal Superoxide Dismutase Transgenic Mice
The neonatal brain is highly susceptible to oxidative stress as developing endogenous antioxidant mechanisms are overwhelmed. In the neonate, superoxide dismutase (SOD) overexpression worsens hypoxic-ischemic injury due to H(2)O(2) accumulation in the brain. Erythropoietin (EPO) is upregulated in 2...
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| Publicado no: | Dev Neurosci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5972513/ https://ncbi.nlm.nih.gov/pubmed/28445874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000472710 |
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