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Erythropoietin Treatment Exacerbates Moderate Injury after Hypoxia-Ischemia in Neonatal Superoxide Dismutase Transgenic Mice

The neonatal brain is highly susceptible to oxidative stress as developing endogenous antioxidant mechanisms are overwhelmed. In the neonate, superoxide dismutase (SOD) overexpression worsens hypoxic-ischemic injury due to H(2)O(2) accumulation in the brain. Erythropoietin (EPO) is upregulated in 2...

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書目詳細資料
發表在:Dev Neurosci
Main Authors: Sheldon, R. Ann, Windsor, Christine, Lee, Byong Sop, Arteaga Cabeza, Olatz, Ferriero, Donna M.
格式: Artigo
語言:Inglês
出版: S. Karger AG 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972513/
https://ncbi.nlm.nih.gov/pubmed/28445874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000472710
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