Carregant...

Humanized Exposures of Cefiderocol, a Siderophore Cephalosporin, Display Sustained in vivo Activity against Siderophore-Resistant Pseudomonas aeruginosa

We evaluated the in vivo efficacy of humanized exposures of cefiderocol, a novel siderophore cephalosporin, against a test panel of P. aeruginosa (PSA) previously shown to develop resistance to 2 preclinical candidate siderophores (MB-1 and SMC-3176). In the thigh infection model, the PSA bacterial...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Pharmacology
Autors principals: Ghazi, Islam M., Monogue, Marguerite L., Tsuji, Masakatsu, Nicolau, David P.
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972512/
https://ncbi.nlm.nih.gov/pubmed/29471305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000487441
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!