Evidence for deleterious hepatitis C virus quasispecies mutation loads that differentiate the response patterns in IFN-based antiviral therapy

Viral quasispecies (QS) have long been considered to affect the efficiency of hepatitis C virus (HCV) antiviral therapy, but a correlation between QS diversity and treatment outcomes has not been established conclusively. We previously measured HCV QS diversity by genome-wide quantification of high-...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Ren, Yi, Wang, Weihua, Zhang, Xiaoan, Xu, Yanjuan, Di Bisceglie, Adrian M., Fan, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2016
Assuntos:
Standard
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972307/
https://ncbi.nlm.nih.gov/pubmed/26581744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000346
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