High-resolution quantification of hepatitis C virus genome-wide mutation load and its correlation with the outcome of peginterferon-alpha2a and ribavirin combination therapy.

Hepatitis C virus (HCV) is a highly mutable RNA virus and circulates as a heterogeneous population in individual patients. The magnitude of such population heterogeneity has long been proposed to be linked with diverse clinical phenotypes, including antiviral therapy. Yet data accumulated thus far a...

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Detaylı Bibliyografya
Asıl Yazarlar: Weihua Wang, Xiaoan Zhang, Yanjuan Xu, George M Weinstock, Adrian M Di Bisceglie, Xiaofeng Fan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2014-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC4065037?pdf=render
Etiketler: Etiketle
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