MicroRNA Let-7f-5p Promotes Bone Marrow Mesenchymal Stem Cells Survival by Targeting Caspase-3 in Alzheimer Disease Model

Widespread death of transplanted mesenchymal stem cells (MSCs) hampers the development of stem cell therapy for Alzheimer disease (AD). Cell pre-conditioning might help cope with this challenge. We tested whether let-7f-5p-modified MSCs could prolong the survival of MSCs after transplantation. When...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Han, Linlin, Zhou, Yan, Zhang, Ruiyi, Wu, Kaimin, Lu, Yanhui, Li, Yanfei, Duan, Ranran, Yao, Yaobing, Zhu, Dengna, Jia, Yanjie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972183/
https://ncbi.nlm.nih.gov/pubmed/29872375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00333
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