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Knockdown of MicroRNA Let-7a Improves the Functionality of Bone Marrow-Derived Mesenchymal Stem Cells in Immunotherapy

Bone marrow-derived mesenchymal stem cells (MSCs) have been recently used in clinical treatment of inflammatory diseases. Practical strategies improving the immunosuppressive property of MSCs are urgently needed for MSC immunotherapy. In this study, we aimed to develop a microRNA-based strategy to i...

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Publicat a:Mol Ther
Autors principals: Yu, Yang, Liao, Li, Shao, Bingyi, Su, Xiaoxia, Shuai, Yi, Wang, Han, Shang, Fengqing, Zhou, Zhifei, Yang, Deqin, Jin, Yan
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368594/
https://ncbi.nlm.nih.gov/pubmed/28153095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.11.015
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