MicroRNA-410 promotes chondrogenic differentiation of human bone marrow mesenchymal stem cells through down-regulating Wnt3a

Background: Chondrogenic differentiation of mesenchymal stem cells (MSCs) is important for osteoarthritis (OA) treatment. However, the specific mechanisms involved are undefined. MicroRNAs (miRNAs) downregulate protein synthesis by binding to the 3’UTR of target mRNA. Methods: Bone marrow aspirates...

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Zhang, Yanjie, Huang, Xiaohan, Yuan, Yanhao
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250710/
https://ncbi.nlm.nih.gov/pubmed/28123640
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