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microRNA-130b downregulation potentiates chondrogenic differentiation of bone marrow mesenchymal stem cells by targeting SOX9

Osteoarthritis (OA) is a chronic health condition. MicroRNAs (miRs) are critical in chondrocyte apoptosis in OA. We aimed to investigate the mechanism of miR-130b in OA progression. Bone marrow mesenchymal stem cells (BMSCs) and chondrocytes were first extracted. Chondrogenic differentiation of BMSC...

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Detalhes bibliográficos
Publicado no:Braz J Med Biol Res
Main Authors: Zhang, Penggui, Gao, Guangming, Zhou, Ziyu, He, Xuejun
Formato: Artigo
Idioma:Inglês
Publicado em: Associação Brasileira de Divulgação Científica 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894390/
https://ncbi.nlm.nih.gov/pubmed/33624729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X202010345
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