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Enantioselective Synthesis of Spliceostatin G and Evaluation of Bioactivity of Spliceostatin G and its Methyl ester

An enantioselective total synthesis of spliceostatin G has been accomplished. The synthesis involved a Suzuki cross-coupling reaction as the key step to construct spliceostatin G. The functionalized tetrahydropyran ring was constructed from commercially available optically active tri-O-acetyl-D-gluc...

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Publicado en:Org Lett
Main Authors: Ghosh, Arun K., Reddy, Guddeti Chandrashekar, MacRae, Andrew J., Jurica, Melissa S.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972028/
https://ncbi.nlm.nih.gov/pubmed/29218995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b03456
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