Comparison of an In Vitro Diagnostic Next-Generation Sequencing Assay with Sanger Sequencing for HIV-1 Genotypic Resistance Testing

The ability of next-generation sequencing (NGS) technologies to detect low frequency HIV-1 drug resistance mutations (DRMs) not detected by dideoxynucleotide Sanger sequencing has potential advantages for improved patient outcomes. We compared the performance of an in vitro diagnostic (IVD) NGS assa...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Tzou, Philip L., Ariyaratne, Pramila, Varghese, Vici, Lee, Charlie, Rakhmanaliev, Elian, Villy, Carolin, Yee, Meiqi, Tan, Kevin, Michel, Gerd, Pinsky, Benjamin A., Shafer, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971553/
https://ncbi.nlm.nih.gov/pubmed/29618499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00105-18
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