Acute loss of iron–sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells

Iron–sulfur (Fe-S) clusters are ancient cofactors in cells and participate in diverse biochemical functions, including electron transfer and enzymatic catalysis. Although cell lines derived from individuals carrying mutations in the Fe-S cluster biogenesis pathway or siRNA-mediated knockdown of the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Crooks, Daniel R., Maio, Nunziata, Lane, Andrew N., Jarnik, Michal, Higashi, Richard M., Haller, Ronald G., Yang, Ye, Fan, Teresa W-M., Linehan, W. Marston, Rouault, Tracey A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2018
Pynciau:
Editors' Picks
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971457/
https://ncbi.nlm.nih.gov/pubmed/29523684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001885
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg