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Altered CREB binding to activity-dependent genes in serine racemase deficient mice, a mouse model of schizophrenia

cAMP-response-element-binding protein (CREB) is a transcription factor ubiquitously expressed in the brain that regulates neuroplasticity by modulating gene expression. The influx of calcium through N-methyl-D-aspartate receptors (NMDARs) is a well-defined mechanism that leads to the increased expre...

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Détails bibliographiques
Publié dans:ACS Chem Neurosci
Auteurs principaux: Balu, Darrick T., Coyle, Joseph T
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971149/
https://ncbi.nlm.nih.gov/pubmed/29172439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00404
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