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The Role of Serine Racemase in the Pathophysiology of Brain Disorders

The N-methyl-D-aspartate receptor (NMDAR) is unique in requiring two agonists to bind simultaneously to open its cation channel: the neurotransmitter, glutamate, and the coagonists, glycine, or D-serine. The Snyder laboratory was the first to clone serine racemase (SR), the enzyme that synthesizes D...

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Detalhes bibliográficos
Publicado no:Adv Pharmacol
Main Authors: Coyle, Joseph T., Balu, Darrick T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821497/
https://ncbi.nlm.nih.gov/pubmed/29413527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apha.2017.10.002
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