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Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction

Schizophrenia is characterized by reduced hippocampal volume, decreased dendritic spine density, altered neuroplasticity signaling pathways, and cognitive deficits associated with impaired hippocampal function. We sought to determine whether this diverse pathology could be linked to NMDA receptor (N...

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Detalhes bibliográficos
Main Authors: Balu, Darrick T., Li, Yan, Puhl, Matthew D., Benneyworth, Michael A., Basu, Alo C., Takagi, Shunsuke, Bolshakov, Vadim Y., Coyle, Joseph T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696825/
https://ncbi.nlm.nih.gov/pubmed/23729812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304308110
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