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Subchronic Pharmacological and Chronic Genetic NMDA Receptor Hypofunction Differentially Regulate the Akt signaling pathway and Arc Expression in Juvenile and Adult mice

NMDA receptor (NMDAR) hypofunction is a compelling hypothesis for the pathophysiology of schizophrenia, because in part, NMDAR antagonists cause symptoms in healthy adult subjects that resemble schizophrenia. Therefore, NMDAR antagonists have been used as a method to induce NMDAR hypofunction in ani...

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Detalhes bibliográficos
Publicado no:Schizophr Res
Main Authors: Takagi, Shunsuke, Balu, Darrick T., Coyle, Joseph T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339465/
https://ncbi.nlm.nih.gov/pubmed/25592804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2014.12.034
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