Genetic variation in genes underlying diverse dementias may explain a small proportion of cases in the Alzheimer’s Disease Sequencing Project

BACKGROUND/AIMS: The Alzheimer’s Disease Sequencing Project (ADSP) aims to identify novel genes influencing Alzheimer’s Disease (AD). Variants within genes known to cause dementias other than AD have been previously associated with AD risk. We describe evidence of co-segregation and association betw...

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Publicado no:Dement Geriatr Cogn Disord
Main Authors: Blue, Elizabeth E., Bis, Joshua C., Dorschner, Michael O., Tsuang, Debby, Barral, Sandra M., Beecham, Gary, Below, Jennifer E., Bush, William S., Butkiewicz, Mariusz, Cruchaga, Carlos, DeStefano, Anita, Farrer, Lindsay A., Goate, Alison, Haines, Jonathan, Jaworski, Jim, Jun, Gyungah, Kunkle, Brian, Kuzma, Amanda, Lee, Jenny J., Lunetta, Kathryn, Ma, Yiyi, Martin, Eden, Naj, Adam, Nato, Andrew Q., Navas, Patrick, Nguyen, Hiep, Reitz, Christiane, Reyes, Dolly, Salerno, William, Schellenberg, Gerard D., Seshadri, Sudha, Sohi, Harkirat, Thornton, Timothy A., Valladares, Otto, van Duijn, Cornelia, Vardarajan, Badri N., Wang, Li-San, Boerwinkle, Eric, Dupuis, Joseé, Pericak-Vance, Margaret A., Mayeux, Richard, Wijsman, Ellen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971141/
https://ncbi.nlm.nih.gov/pubmed/29486463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000485503
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